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Who needs a helium-recovery system?

January 16, 2025

By Adam Brown and Michael O'Herron

Why laboratories, universities, and hospitals want to recapture this critical raw material

A version of this blog first appeared as “Who needs a helium-recovery system?” in Design Quarterly, Issue 23.

Before you pop that floating balloon after midnight on New Year’s Eve, give this some thought: Once the lightweight gas leaves that balloon, it’s never coming back.

Helium (named for Helios, Greek god of the Sun) is small and light enough to escape from the atmosphere and into space. These days, we use helium for a lot more than birthday parties and parade inflatables. And it’s getting expensive. That has a lot of its significant users looking at helium-recovery systems.

Helium is good at conducting heat. And it has the lowest boiling point of any known material, which makes it a great coolant for things that must be kept very cold.

Let’s dig into helium uses, its supply, and why a helium-recovery system might be a wise investment.

US consumption of Grade-A and gaseous helium in 2023. (Source: U.S. Geological Survey)

What is helium used for?

Superconducting magnets: We can use helium to cool these magnets. When cooled with liquid helium, certain types of electromagnets allow electricity to flow through them with no resistance. In hospitals, magnetic resonance imaging (MRI) scanners use superconducting magnets. University and industry research laboratories use helium as they develop new drugs. Today, we use most of our helium in these types of cryogenic applications. For example, Pfizer’s Pharmaceutical Sciences division (PharmSci) uses NMRs (nuclear magnetic resonance) to characterize and study potential new active pharmaceutical ingredients, or APIs.

Space, science, and welding: The space industry is a major consumer, using helium to expel liquid rocket fuel for combustion. And because it conducts heat well, it offers good penetration and faster speed for welders. Because it’s nonreactive, it makes a good shielding gas, protecting the arc from oxygen and contaminants. It's used in science to cool particle accelerators and quantum computers. The Large Hadron Collider uses massive quantities of helium. And NASA’s James Webb Space Telescope uses a helium cryogenic cooler to ensure its infrared sensors work.

Semiconductors: Extreme vacuum conditions are needed to build semiconductors. Even tiny leaks can ruin the product. Helium is preferred for detection because it is small enough to reliably find leaks, is inert, and nontoxic. It is also still relatively cheap when compared to other noble gases. And with only very small quantities in the atmosphere, ambient helium won’t distort measurements.

Where does Earth’s helium come from?

Helium is a naturally occurring byproduct of radioactive material in the earth. Found underground, it’s mined in just a few places. It’s usually harvested as a byproduct from oil and natural gas production. It’s a nonrenewable resource on Earth. The radioactive decay of uranium that produces it takes an awful long time.

The supply is limited. So, back to our party balloons. Honestly, not much helium is used in them—just 5-7 percent, according to the balloon industry. But that’s still helium that’s gone once it’s used.

Helium is used in a variety of ways. Some of those ways include superconducting magnets, manufacture of semiconductors, welding, and in pharmaceutical labs.

Helium prices are going up

Up until recently, helium was fairly cheap and considered abundant. But the US is producing less even as demand rises—and only a few countries harvest it. So, the price of helium is extra sensitive. It can be impacted by regional conflict, trade wars, and accidents at helium plants.

The price surged in 2022 and 2023. With the cost of new helium rising, customers are looking for alternative ways to reduce costs.

Reducing helium costs

Researchers are looking for alternative processes and materials. They want to reduce or eliminate helium in superconducting, cooling, leak-testing, and in MRIs. For cryogens, however, helium will remain in use., So users need ways to reduce their use.

Closed-loop systems are one method larger consumers can use to reduce their helium budget. For example, the U.S. Department of Energy’s Linac Coherent Light Source-II at Stanford University in California circulates four tons of helium with low losses. Hospitals, labs, and drug manufacturers that use virgin helium could benefit from finding ways to recapture it. Retrofitting existing equipment with a helium-recovery system can reduce the helium that escapes from their facility. This can bring down their annual bills and likely pay for itself in a decade or less.

Retrofitting existing equipment with a helium-recovery system can reduce the helium that escapes from their facility. This can … likely pay for itself in a decade or less.

How does a helium-recovery system work?

We recently finished the design for a facility modification to support a new helium-recovery system for a pharmaceutical maker. The company uses dozens of NMRs in its labs. The technology in the helium-recovery system is not new. The bespoke system, aggregated to a complete system by Bruker BioSpin, combines a number of off-the-shelf products from several manufacturers. Our team’s job was to integrate the system design into the available space.

The new recapture system connects to a series of NMRs distributed across eight labs on four floors. The helium-recovery system collects the helium venting off the NMR magnets in a large neoprene balloon. It then compresses, purifies, and liquifies the helium for reuse in the magnets.

There are, of course, challenges to designing these systems. Space and power are two of them.

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HelioSmart Liquefaction system by Bruker BioSpin with components from Quantum Design and Bauer. (Diagram courtesy of Bruker.) Elements include: A. Customer instruments; B. Helium gas balloon including controller; C. High-pressure compressor; D. High-pressure helium gas cylinders; E. Pressure reducer; F. Dryer; G. Purifier ATP30; H. Compressor F70/FA40 for purifier; I. Liquefier NexGen250; J. Compressor HLC 4900H for liquefier.

Space: The facility must hold a helium-recovery system that can include a large storage balloon, a compressor, a liquefier, a purifier, and storage tanks. Liquid helium’s boiling point in the magnet is affected by pressure changes, and this can influence research results. To mitigate those effects, the recovery system uses a large low-pressure reservoir to capture the helium.

A deflated balloon gradually fills with helium at low pressure. Next, the system compresses the helium and collects it in high-pressure storage tanks. This reduces the volume. Once the tanks collect enough compressed helium, the system passes it to a purifier and liquefier. Ultimately, it captures the liquid helium in a vacuum-insulated dewar flask, which can be used to refill the magnet’s supply.

Power: The recapture process needs a lot of energy. The compressors required to purify and liquefy the helium use a great amount of electricity. So, a helium-recovery system will need a lot of power.

When considering the cost of system installation, we need to account for the cost of adding or upgrading electrical services required for the new loads.

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The price of helium surged in 2022 and 2023, and there are just a few nations that harvest it.

Who are the best candidates for helium recapture?

Recapture systems make sense for pharmaceutical labs using NMRs, hospitals using MRIs, and research facilities. These facilities use large amounts of helium in a fixed, well-insulated location that has a low boil-off rate. These fixed location facilities lend themselves to the use of a helium-recovery system.

Anticipated payback time for helium recovery systems

With the cost of helium rising, the payback time for investment in a helium-recovery system is shrinking. The most significant users of helium would be wise to investigate setting up a recovery system to control long-term costs.

The return on investment is a good argument for helium-recovery systems. Sustainability is another. Helium is a precious resource that plays a vital role in medicine, advanced science, and research. The Earth has a limited supply. We should look at implementing helium-recovery systems wherever the scale of helium usage will justify the investment.

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  • Adam Brown

    A process engineering discipline lead and chemical engineer, Adam has experience in providing engineering design and support for projects in the pharmaceutical, food, wastewater, and fine chemical industries.

    Contact Adam
  • Michael O'Herron

    Michael is a process designer with over 15 years of experience in various sectors who has a deep understanding of how systems function, from both a business and engineering perspective.

    Contact Michael
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